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Large-scale analysis of chromosomal aberrations in cancer karyotypes reveals two distinct paths to aneuploidy

BACKGROUND: Chromosomal aneuploidy, that is to say the gain or loss of chromosomes, is the most common abnormality in cancer. While certain aberrations, most commonly translocations, are known to be strongly associated with specific cancers and contribute to their formation, most aberrations appear...

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Detalles Bibliográficos
Autores principales: Ozery-Flato, Michal, Linhart, Chaim, Trakhtenbrot, Luba, Izraeli, Shai, Shamir, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218849/
https://www.ncbi.nlm.nih.gov/pubmed/21714908
http://dx.doi.org/10.1186/gb-2011-12-6-r61