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Large-scale analysis of chromosomal aberrations in cancer karyotypes reveals two distinct paths to aneuploidy
BACKGROUND: Chromosomal aneuploidy, that is to say the gain or loss of chromosomes, is the most common abnormality in cancer. While certain aberrations, most commonly translocations, are known to be strongly associated with specific cancers and contribute to their formation, most aberrations appear...
Autores principales: | Ozery-Flato, Michal, Linhart, Chaim, Trakhtenbrot, Luba, Izraeli, Shai, Shamir, Ron |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218849/ https://www.ncbi.nlm.nih.gov/pubmed/21714908 http://dx.doi.org/10.1186/gb-2011-12-6-r61 |
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