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Identification of new autoantibody specificities directed at proteins involved in the transforming growth factor β pathway in patients with systemic sclerosis

INTRODUCTION: Antinuclear antibodies (ANAs), usually detected by indirect immunofluorescence on HEp-2 cells, are identified in 90% of patients with systemic sclerosis (SSc). Thus, approximately 10% of SSc patients have no routinely detectable autoantibodies, and for 20% to 40% of those with detectab...

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Detalles Bibliográficos
Autores principales: Bussone, Guillaume, Dib, Hanadi, Tamby, Mathieu C, Broussard, Cedric, Federici, Christian, Woimant, Geneviève, Camoin, Luc, Guillevin, Loïc, Mouthon, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218884/
https://www.ncbi.nlm.nih.gov/pubmed/21569507
http://dx.doi.org/10.1186/ar3336