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Infliximab in ankylosing spondylitis: alone or in combination with methotrexate? A pharmacokinetic comparative study

INTRODUCTION: Methotrexate (MTX) has been shown to modify infliximab pharmacokinetics in rheumatoid arthritis. However, its combination with infliximab in the treatment of ankylosing spondylitis (AS) is not recommended. The objective of this study was to examine the influence of MTX on infliximab ex...

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Detalles Bibliográficos
Autores principales: Mulleman, Denis, Lauféron, Francine, Wendling, Daniel, Ternant, David, Ducourau, Emilie, Paintaud, Gilles, Goupille, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218893/
https://www.ncbi.nlm.nih.gov/pubmed/21639907
http://dx.doi.org/10.1186/ar3350