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EZH2-mediated epigenetic repression of DNA repair in promoting breast tumor initiating cells
Members of the Polycomb-group (PcG) family of proteins, including EZH2 (enhancer of zeste homolog 2), are involved in establishing epigenetic silencing of developmental genes in adult and embryonic stem cells, and their deregulation has been implicated in cancer. In a recent report, EZH2-mediated ep...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218929/ https://www.ncbi.nlm.nih.gov/pubmed/21672285 http://dx.doi.org/10.1186/bcr2871 |