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Notch signaling as a therapeutic target for breast cancer treatment?

Aberrant Notch signaling can induce mammary gland carcinoma in transgenic mice, and high expressions of Notch receptors and ligands have been linked to poor clinical outcomes in human patients with breast cancer. This suggests that inhibition of Notch signaling may be beneficial for breast cancer tr...

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Detalles Bibliográficos
Autores principales: Han, Jianxun, Hendzel, Michael J, Allalunis-Turner, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218932/
https://www.ncbi.nlm.nih.gov/pubmed/21672271
http://dx.doi.org/10.1186/bcr2875