Breast cancer growth and metastasis: interplay between cancer stem cells, embryonic signaling pathways and epithelial-to-mesenchymal transition

Induction of epithelial-to-mesenchymal transition (EMT) in cancer stem cells (CSCs) can occur as the result of embryonic pathway signaling. Activation of Hedgehog (Hh), Wnt, Notch, or transforming growth factor-β leads to the upregulation of a group of transcriptional factors that drive EMT. This pr...

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Detalles Bibliográficos
Autores principales: Takebe, Naoko, Warren, Ronald Q, Ivy, S Percy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218933/
https://www.ncbi.nlm.nih.gov/pubmed/21672282
http://dx.doi.org/10.1186/bcr2876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218933/
https://www.ncbi.nlm.nih.gov/pubmed/21672282
http://dx.doi.org/10.1186/bcr2876

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