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Glucocorticoids in sepsis: dissecting facts from fiction

An intact hypothalamic-pituitary-adrenal (HPA) axis with effective intracellular glucocorticoid anti-inflammatory activity is essential for host survival following exposure to an infectious agent. Glucocorticoids play a major role in regulating the activity of nuclear factorkappa- B, which has a cru...

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Detalles Bibliográficos
Autor principal: Marik, Paul E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218964/
https://www.ncbi.nlm.nih.gov/pubmed/21586102
http://dx.doi.org/10.1186/cc10101