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Dexmedetomidine provides renoprotection against ischemia-reperfusion injury in mice

INTRODUCTION: Acute kidney injury following surgery incurs significant mortality with no proven preventative therapy. We investigated whether the α(2 )adrenoceptor agonist dexmedetomidine (Dex) provides protection against ischemia-reperfusion induced kidney injury in vitro and in vivo. METHODS: In v...

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Detalles Bibliográficos
Autores principales: Gu, Jianteng, Sun, Pamela, Zhao, Hailin, Watts, Helena R, Sanders, Robert D, Terrando, Niccolo, Xia, Peiyuan, Maze, Mervyn, Ma, Daqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219027/
https://www.ncbi.nlm.nih.gov/pubmed/21702944
http://dx.doi.org/10.1186/cc10283