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Personalizing carbamazepine therapy

The anticonvulsant carbamazepine has a high incidence of cutaneous adverse drug reactions. A recent prospective clinical trial in Taiwan has indicated that HLA-B*1502 screening will reduce the incidence of life-threatening adverse reactions to carbamazepine, while a genome-wide association study has...

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Detalles Bibliográficos
Autores principales: Mushiroda, Taisei, Nakamura, Yusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219069/
https://www.ncbi.nlm.nih.gov/pubmed/21635710
http://dx.doi.org/10.1186/gm243