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Transcriptome instability in colorectal cancer identified by exon microarray analyses: Associations with splicing factor expression levels and patient survival

BACKGROUND: Colorectal cancer (CRC) is a heterogeneous disease that, on the molecular level, can be characterized by inherent genomic instabilities; chromosome instability and microsatellite instability. In the present study we analyze genome-wide disruption of pre-mRNA splicing, and propose transcr...

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Detalles Bibliográficos
Autores principales: Sveen, Anita, Ågesen, Trude H, Nesbakken, Arild, Rognum, Torleiv O, Lothe, Ragnhild A, Skotheim, Rolf I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219073/
https://www.ncbi.nlm.nih.gov/pubmed/21619627
http://dx.doi.org/10.1186/gm248