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The tumour-suppressive function of CLU is explained by its localisation and interaction with HSP60
The product of the CLU gene promotes or inhibits tumourigenesis in a context-dependent manner. It has been hypothesised that different CLU isoforms have different and even opposing biological functions, but this theory has not been experimentally validated. Here we show that molecules involved in su...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219095/ https://www.ncbi.nlm.nih.gov/pubmed/22012253 http://dx.doi.org/10.1038/cddis.2011.99 |