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The tumour-suppressive function of CLU is explained by its localisation and interaction with HSP60

The product of the CLU gene promotes or inhibits tumourigenesis in a context-dependent manner. It has been hypothesised that different CLU isoforms have different and even opposing biological functions, but this theory has not been experimentally validated. Here we show that molecules involved in su...

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Detalles Bibliográficos
Autores principales: Chaiwatanasirikul, K-A, Sala, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219095/
https://www.ncbi.nlm.nih.gov/pubmed/22012253
http://dx.doi.org/10.1038/cddis.2011.99