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Alternative TFAP2A isoforms have distinct activities in breast cancer

INTRODUCTION: AP-2α is a transcription factor implicated in the regulation of differentiation and proliferation in certain tissues, including the mammary gland. In breast tumours, continued expression of AP-2α has been correlated with a better prognosis, but this is hard to reconcile with a reported...

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Detalles Bibliográficos
Autores principales: Berlato, Chiara, Chan, KaYi V, Price, Anna M, Canosa, Monica, Scibetta, Angelo G, Hurst, Helen C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219183/
https://www.ncbi.nlm.nih.gov/pubmed/21375726
http://dx.doi.org/10.1186/bcr2838