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Fulvestrant-induced expression of ErbB3 and ErbB4 receptors sensitizes oestrogen receptor-positive breast cancer cells to heregulin β1

INTRODUCTION: We have previously reported that induction of epidermal growth factor receptor and ErbB2 in response to antihormonal agents may provide an early mechanism to allow breast cancer cells to evade the growth-inhibitory action of such therapies and ultimately drive resistant cell growth. Mo...

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Detalles Bibliográficos
Autores principales: Hutcheson, Iain R, Goddard, Lindy, Barrow, Denise, McClelland, Richard A, Francies, Hayley E, Knowlden, Janice M, Nicholson, Robert I, Gee, Julia MW
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219190/
https://www.ncbi.nlm.nih.gov/pubmed/21396094
http://dx.doi.org/10.1186/bcr2848