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Estrogen receptor beta inhibits transcriptional activity of hypoxia inducible factor-1 through the downregulation of arylhydrocarbon receptor nuclear translocator

INTRODUCTION: Estrogen receptor (ER) β is predicted to play an important role in prevention of breast cancer development and metastasis. We have shown previously that ERβ inhibits hypoxia inducible factor (HIF)-1α mediated transcription, but the mechanism by which ERβ works to exert this effect is n...

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Detalles Bibliográficos
Autores principales: Lim, Wonchung, Park, Yeomyung, Cho, Jungyoon, Park, Choa, Park, Joonwoo, Park, Young-Kwon, Park, Hyunsung, Lee, YoungJoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219195/
https://www.ncbi.nlm.nih.gov/pubmed/21435239
http://dx.doi.org/10.1186/bcr2854