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Mutations in the epidermal growth factor receptor (EGFR) gene in triple negative breast cancer: possible implications for targeted therapy

INTRODUCTION: Triple negative breast cancer is associated with poorer prognosis and unresponsiveness to endocrine and anti-HER2 directed agents. Despite emerging data supporting the use of polyADP-ribose polymerase (PARP) inhibitors, complete and durable responses are rare and exploration of additio...

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Detalles Bibliográficos
Autores principales: Teng, Yvonne Hui-Fang, Tan, Wai-Jin, Thike, Aye-Aye, Cheok, Poh-Yian, Tse, Gary Man-Kit, Wong, Nan-Soon, Yip, George Wai-Cheong, Bay, Boon-Huat, Tan, Puay-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219198/
https://www.ncbi.nlm.nih.gov/pubmed/21457545
http://dx.doi.org/10.1186/bcr2857