Quantitative assays for the measurement of HER1-HER2 heterodimerization and phosphorylation in cell lines and breast tumors: applications for diagnostics and targeted drug mechanism of action

INTRODUCTION: Ligand-bound and phosphorylated ErbB/HER heterodimers are potent signaling forms of this receptor family, and quantitative measurements of these active receptors may be predictive of patient response to targeted therapies. Using VeraTag™ technology, we developed and characterized quant...

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Detalles Bibliográficos
Autores principales: DeFazio-Eli, Lisa, Strommen, Kristi, Dao-Pick, Trang, Parry, Gordon, Goodman, Laurie, Winslow, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219207/
https://www.ncbi.nlm.nih.gov/pubmed/21496232
http://dx.doi.org/10.1186/bcr2866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219207/
https://www.ncbi.nlm.nih.gov/pubmed/21496232
http://dx.doi.org/10.1186/bcr2866

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