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Circulating retinol binding protein 4 in critically ill patients before specific treatment: prognostic impact and correlation with organ function, metabolism and inflammation

INTRODUCTION: Hyperglycemia and insulin resistance are well-known features of critical illness and impact the mortality rate, especially in sepsis. Retinol binding protein 4 (RBP4) promotes insulin resistance in mice and is systemically elevated in patients with obesity and type 2 diabetes. We inves...

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Detalles Bibliográficos
Autores principales: Koch, Alexander, Weiskirchen, Ralf, Sanson, Edouard, Zimmermann, Henning W, Voigt, Sebastian, Dückers, Hanna, Trautwein, Christian, Tacke, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219283/
https://www.ncbi.nlm.nih.gov/pubmed/20932285
http://dx.doi.org/10.1186/cc9285