The proteasomal inhibitor MG132 prevents muscular dystrophy in zebrafish

Using sapje zebrafish which lack dystrophin, we have assessed both the quantitation of muscle damage in dystrophic fish, and the efficacy of the proteasomal inhibitor MG132 in reducing the dystrophic symptoms. Fourier analysis of birefringence patterns in normal and dystrophic fish was found to be a...

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Detalles Bibliográficos
Autores principales: Winder, Steve J, Lipscomb, Leanne, Angela Parkin, Caroline, Juusola, Mikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Muscular Dystrophy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219425/
https://www.ncbi.nlm.nih.gov/pubmed/22130468
http://dx.doi.org/10.1371/currents.RRN1286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219425/
https://www.ncbi.nlm.nih.gov/pubmed/22130468
http://dx.doi.org/10.1371/currents.RRN1286

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