Glucose deprivation in tuberous sclerosis complex-related tumors

BACKGROUND: Cancer cells possess unique metabolic phenotypes that are determined by their underlying oncogenic pathways. Activation of the PI3K/Akt/mTOR signaling cascade promotes glycolysis and leads to glucose-dependence in tumors. In particular, cells with constitutive mTORC1 activity secondary t...

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Detalles Bibliográficos
Autores principales: Jiang, Xiuyun, Kenerson, Heidi L, Yeung, Raymond S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219560/
https://www.ncbi.nlm.nih.gov/pubmed/22018000
http://dx.doi.org/10.1186/2045-3701-1-34

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219560/
https://www.ncbi.nlm.nih.gov/pubmed/22018000
http://dx.doi.org/10.1186/2045-3701-1-34

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