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Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression

BACKGROUND: There is a pressing need to identify novel pathophysiological pathways relevant to depression that can help to reveal targets for the development of new medications. Toll-like receptor 4 (TLR-4) has a regulatory role in the brain's response to stress. Psychological stress may compro...

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Detalles Bibliográficos
Autores principales: Gárate, Iciar, García-Bueno, Borja, Madrigal, José LM, Bravo, Lidia, Berrocoso, Esther, Caso, Javier R, Micó, Juan A, Leza, Juan C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219571/
https://www.ncbi.nlm.nih.gov/pubmed/22053929
http://dx.doi.org/10.1186/1742-2094-8-151