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PBX1 Genomic Pioneer Function Drives ERα Signaling Underlying Progression in Breast Cancer
Altered transcriptional programs are a hallmark of diseases, yet how these are established is still ill-defined. PBX1 is a TALE homeodomain protein involved in the development of different types of cancers. The estrogen receptor alpha (ERα) is central to the development of two-thirds of all breast c...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219601/ https://www.ncbi.nlm.nih.gov/pubmed/22125492 http://dx.doi.org/10.1371/journal.pgen.1002368 |