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PBX1 Genomic Pioneer Function Drives ERα Signaling Underlying Progression in Breast Cancer

Altered transcriptional programs are a hallmark of diseases, yet how these are established is still ill-defined. PBX1 is a TALE homeodomain protein involved in the development of different types of cancers. The estrogen receptor alpha (ERα) is central to the development of two-thirds of all breast c...

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Detalles Bibliográficos
Autores principales: Magnani, Luca, Ballantyne, Elizabeth B., Zhang, Xiaoyang, Lupien, Mathieu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219601/
https://www.ncbi.nlm.nih.gov/pubmed/22125492
http://dx.doi.org/10.1371/journal.pgen.1002368