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Secondhand smoke exposure induces Raf/ERK/MAPK-mediated upregulation of cerebrovascular endothelin ET(A )receptors

BACKGROUND: Cigarette smoking enhances the risk of stroke. However, the underlying molecular mechanisms are largely unknown. The present study established an in vivo rat secondhand cigarette smoking (SHS) model and examined the hypothesis that SHS upregulates endothelin receptors with increased cere...

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Detalles Bibliográficos
Autores principales: Cao, Lei, Xu, Cang-Bao, Zhang, Yaping, Cao, Yong-Xiao, Edvinsson, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219602/
https://www.ncbi.nlm.nih.gov/pubmed/22044770
http://dx.doi.org/10.1186/1471-2202-12-109