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Virus Replication Strategies and the Critical CTL Numbers Required for the Control of Infection

Vaccines that elicit protective cytotoxic T lymphocytes (CTL) may improve on or augment those designed primarily to elicit antibody responses. However, we have little basis for estimating the numbers of CTL required for sterilising immunity at an infection site. To address this we begin with a theor...

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Detalles Bibliográficos
Autores principales: Yates, Andrew J., Van Baalen, Minus, Antia, Rustom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219614/
https://www.ncbi.nlm.nih.gov/pubmed/22125483
http://dx.doi.org/10.1371/journal.pcbi.1002274