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Construction and Analysis of an Integrated Regulatory Network Derived from High-Throughput Sequencing Data
We present a network framework for analyzing multi-level regulation in higher eukaryotes based on systematic integration of various high-throughput datasets. The network, namely the integrated regulatory network, consists of three major types of regulation: TF→gene, TF→miRNA and miRNA→gene. We ident...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219617/ https://www.ncbi.nlm.nih.gov/pubmed/22125477 http://dx.doi.org/10.1371/journal.pcbi.1002190 |