Speed, Sensitivity, and Bistability in Auto-activating Signaling Circuits

Cells employ a myriad of signaling circuits to detect environmental signals and drive specific gene expression responses. A common motif in these circuits is inducible auto-activation: a transcription factor that activates its own transcription upon activation by a ligand or by post-transcriptional...

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Detalles Bibliográficos
Autores principales: Hermsen, Rutger, Erickson, David W., Hwa, Terence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219618/
https://www.ncbi.nlm.nih.gov/pubmed/22125482
http://dx.doi.org/10.1371/journal.pcbi.1002265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219618/
https://www.ncbi.nlm.nih.gov/pubmed/22125482
http://dx.doi.org/10.1371/journal.pcbi.1002265

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