Transforming Growth Factor β(1) Oppositely Regulates the Hypertrophic and Contractile Response to β-Adrenergic Stimulation in the Heart

BACKGROUND: Neuroendocrine activation and local mediators such as transforming growth factor-β(1) (TGF-β(1)) contribute to the pathobiology of cardiac hypertrophy and failure, but the underlying mechanisms are incompletely understood. We aimed to characterize the functional network involving TGF-β(1...

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Detalles Bibliográficos
Autores principales: Huntgeburth, Michael, Tiemann, Klaus, Shahverdyan, Robert, Schlüter, Klaus-Dieter, Schreckenberg, Rolf, Gross, Marie-Luise, Mödersheim, Sonja, Caglayan, Evren, Müller-Ehmsen, Jochen, Ghanem, Alexander, Vantler, Marius, Zimmermann, Wolfram H., Böhm, Michael, Rosenkranz, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219639/
https://www.ncbi.nlm.nih.gov/pubmed/22125598
http://dx.doi.org/10.1371/journal.pone.0026628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219639/
https://www.ncbi.nlm.nih.gov/pubmed/22125598
http://dx.doi.org/10.1371/journal.pone.0026628

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