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Transforming Growth Factor β(1) Oppositely Regulates the Hypertrophic and Contractile Response to β-Adrenergic Stimulation in the Heart
BACKGROUND: Neuroendocrine activation and local mediators such as transforming growth factor-β(1) (TGF-β(1)) contribute to the pathobiology of cardiac hypertrophy and failure, but the underlying mechanisms are incompletely understood. We aimed to characterize the functional network involving TGF-β(1...
Autores principales: | Huntgeburth, Michael, Tiemann, Klaus, Shahverdyan, Robert, Schlüter, Klaus-Dieter, Schreckenberg, Rolf, Gross, Marie-Luise, Mödersheim, Sonja, Caglayan, Evren, Müller-Ehmsen, Jochen, Ghanem, Alexander, Vantler, Marius, Zimmermann, Wolfram H., Böhm, Michael, Rosenkranz, Stephan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219639/ https://www.ncbi.nlm.nih.gov/pubmed/22125598 http://dx.doi.org/10.1371/journal.pone.0026628 |
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