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Overlooking Evolution: A Systematic Analysis of Cancer Relapse and Therapeutic Resistance Research

Cancer therapy selects for cancer cells resistant to treatment, a process that is fundamentally evolutionary. To what extent, however, is the evolutionary perspective employed in research on therapeutic resistance and relapse? We analyzed 6,228 papers on therapeutic resistance and/or relapse in canc...

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Detalles Bibliográficos
Autores principales: Aktipis, C. Athena, Kwan, Virginia S. Y., Johnson, Kathryn A., Neuberg, Steven L., Maley, Carlo C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219640/
https://www.ncbi.nlm.nih.gov/pubmed/22125594
http://dx.doi.org/10.1371/journal.pone.0026100