Crosstalk between ROS Homeostasis and Secondary Metabolism in S. natalensis ATCC 27448: Modulation of Pimaricin Production by Intracellular ROS

Streptomyces secondary metabolism is strongly affected by oxygen availability. The increased culture aeration enhances pimaricin production in S. natalensis, however the excess of O(2) consumption can lead to an intracellular ROS imbalance that is harmful to the cell. The adaptive physiological resp...

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Detalles Bibliográficos
Autores principales: Beites, Tiago, Pires, Sílvia D. S., Santos, Catarina L., Osório, Hugo, Moradas-Ferreira, Pedro, Mendes, Marta V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219662/
https://www.ncbi.nlm.nih.gov/pubmed/22114674
http://dx.doi.org/10.1371/journal.pone.0027472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219662/
https://www.ncbi.nlm.nih.gov/pubmed/22114674
http://dx.doi.org/10.1371/journal.pone.0027472

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