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Isoflurane-Induced Spatial Memory Impairment in Mice is Prevented by the Acetylcholinesterase Inhibitor Donepezil

Although many studies have shown that isoflurane exposure impairs spatial memory in aged animals, there are no clinical treatments available to prevent this memory deficit. The anticholinergic properties of volatile anesthetics are a biologically plausible cause of cognitive dysfunction in elderly s...

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Detalles Bibliográficos
Autores principales: Su, Diansan, Zhao, Yanxing, Wang, Beilei, Xu, Huan, Li, Wen, Chen, Jie, Wang, Xiangrui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219671/
https://www.ncbi.nlm.nih.gov/pubmed/22114680
http://dx.doi.org/10.1371/journal.pone.0027632