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Isoflurane-Induced Spatial Memory Impairment in Mice is Prevented by the Acetylcholinesterase Inhibitor Donepezil
Although many studies have shown that isoflurane exposure impairs spatial memory in aged animals, there are no clinical treatments available to prevent this memory deficit. The anticholinergic properties of volatile anesthetics are a biologically plausible cause of cognitive dysfunction in elderly s...
Autores principales: | Su, Diansan, Zhao, Yanxing, Wang, Beilei, Xu, Huan, Li, Wen, Chen, Jie, Wang, Xiangrui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219671/ https://www.ncbi.nlm.nih.gov/pubmed/22114680 http://dx.doi.org/10.1371/journal.pone.0027632 |
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