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The N-Terminal Domain and Glycosomal Localization of Leishmania Initial Acyltransferase LmDAT Are Important for Lipophosphoglycan Synthesis

Ether glycerolipids of Leishmania major are important membrane components as well as building blocks of various virulence factors. In L. major, the first enzyme of the ether glycerolipid biosynthetic pathway, LmDAT, is an unusual, glycosomal dihydroxyacetonephosphate acyltransferase important for pa...

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Detalles Bibliográficos
Autores principales: Al-Ani, Gada K., Patel, Nipul, Pirani, Karim A., Zhu, Tongtong, Dhalladoo, Subbhalakshmi, Zufferey, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219689/
https://www.ncbi.nlm.nih.gov/pubmed/22114698
http://dx.doi.org/10.1371/journal.pone.0027802