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The N-Terminal Domain and Glycosomal Localization of Leishmania Initial Acyltransferase LmDAT Are Important for Lipophosphoglycan Synthesis
Ether glycerolipids of Leishmania major are important membrane components as well as building blocks of various virulence factors. In L. major, the first enzyme of the ether glycerolipid biosynthetic pathway, LmDAT, is an unusual, glycosomal dihydroxyacetonephosphate acyltransferase important for pa...
Autores principales: | Al-Ani, Gada K., Patel, Nipul, Pirani, Karim A., Zhu, Tongtong, Dhalladoo, Subbhalakshmi, Zufferey, Rachel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219689/ https://www.ncbi.nlm.nih.gov/pubmed/22114698 http://dx.doi.org/10.1371/journal.pone.0027802 |
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