Essential Role of the Small GTPase Ran in Postnatal Pancreatic Islet Development

The small GTPase Ran orchestrates pleiotropic cellular responses of nucleo-cytoplasmic shuttling, mitosis and subcellular trafficking, but whether deregulation of these pathways contributes to disease pathogenesis has remained elusive. Here, we generated transgenic mice expressing wild type (WT) Ran...

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Detalles Bibliográficos
Autores principales: Xia, Fang, Dohi, Takehiko, Martin, Nina M., Raskett, Christopher M., Liu, Qin, Altieri, Dario C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219697/
https://www.ncbi.nlm.nih.gov/pubmed/22114719
http://dx.doi.org/10.1371/journal.pone.0027879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219697/
https://www.ncbi.nlm.nih.gov/pubmed/22114719
http://dx.doi.org/10.1371/journal.pone.0027879

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