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Deletion of Cryptococcus neoformans AIF Ortholog Promotes Chromosome Aneuploidy and Fluconazole-Resistance in a Metacaspase-Independent Manner

Apoptosis is a form of programmed cell death critical for development and homeostasis in multicellular organisms. Apoptosis-like cell death (ALCD) has been described in several fungi, including the opportunistic human pathogen Cryptococcus neoformans. In addition, capsular polysaccharides of C. neof...

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Detalles Bibliográficos
Autores principales: Semighini, Camile P., Averette, Anna F., Perfect, John R., Heitman, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219705/
https://www.ncbi.nlm.nih.gov/pubmed/22114551
http://dx.doi.org/10.1371/journal.ppat.1002364