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Structure-Based Vaccines Provide Protection in a Mouse Model of Ehrlichiosis

BACKGROUND: Recent advances in bioinformatics have made it possible to predict the B cell and T cell epitopes of antigenic proteins. This has led to design of peptide based vaccines that are more specific, safe, and easy to produce. The obligately intracellular gram negative bacteria Ehrlichia cause...

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Detalles Bibliográficos
Autores principales: Thomas, Sunil, Thirumalapura, Nagaraja R., Crocquet-Valdes, Patricia A., Luxon, Bruce A., Walker, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219711/
https://www.ncbi.nlm.nih.gov/pubmed/22114733
http://dx.doi.org/10.1371/journal.pone.0027981