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Structure-Based Vaccines Provide Protection in a Mouse Model of Ehrlichiosis
BACKGROUND: Recent advances in bioinformatics have made it possible to predict the B cell and T cell epitopes of antigenic proteins. This has led to design of peptide based vaccines that are more specific, safe, and easy to produce. The obligately intracellular gram negative bacteria Ehrlichia cause...
Autores principales: | Thomas, Sunil, Thirumalapura, Nagaraja R., Crocquet-Valdes, Patricia A., Luxon, Bruce A., Walker, David H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219711/ https://www.ncbi.nlm.nih.gov/pubmed/22114733 http://dx.doi.org/10.1371/journal.pone.0027981 |
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