A Gammaherpesvirus Cooperates with Interferon-alpha/beta-Induced IRF2 to Halt Viral Replication, Control Reactivation, and Minimize Host Lethality

The gammaherpesviruses, including Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV), establish latency in memory B lymphocytes and promote lymphoproliferative disease in immunocompromised individuals. The precise immune mechanisms that prevent gammaherpesvirus reactiva...

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Detalles Bibliográficos
Autores principales: Mandal, Pratyusha, Krueger, Bridgette E., Oldenburg, Darby, Andry, Katherine A., Beard, R. Suzanne, White, Douglas W., Barton, Erik S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219715/
https://www.ncbi.nlm.nih.gov/pubmed/22114555
http://dx.doi.org/10.1371/journal.ppat.1002371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219715/
https://www.ncbi.nlm.nih.gov/pubmed/22114555
http://dx.doi.org/10.1371/journal.ppat.1002371

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