SH3 Domain-Mediated Recruitment of Host Cell Amphiphysins by Alphavirus nsP3 Promotes Viral RNA Replication

Among the four non-structural proteins of alphaviruses the function of nsP3 is the least well understood. NsP3 is a component of the viral replication complex, and composed of a conserved aminoterminal macro domain implicated in viral RNA synthesis, and a poorly conserved carboxyterminal region. Des...

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Detalles Bibliográficos
Autores principales: Neuvonen, Maarit, Kazlauskas, Arunas, Martikainen, Miika, Hinkkanen, Ari, Ahola, Tero, Saksela, Kalle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219718/
https://www.ncbi.nlm.nih.gov/pubmed/22114558
http://dx.doi.org/10.1371/journal.ppat.1002383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219718/
https://www.ncbi.nlm.nih.gov/pubmed/22114558
http://dx.doi.org/10.1371/journal.ppat.1002383

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