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Neurons are MHC Class I-Dependent Targets for CD8 T Cells upon Neurotropic Viral Infection

Following infection of the central nervous system (CNS), the immune system is faced with the challenge of eliminating the pathogen without causing significant damage to neurons, which have limited capacities of renewal. In particular, it was thought that neurons were protected from direct attack by...

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Detalles Bibliográficos
Autores principales: Chevalier, Grégoire, Suberbielle, Elsa, Monnet, Céline, Duplan, Valérie, Martin-Blondel, Guillaume, Farrugia, Fanny, Le Masson, Gwendal, Liblau, Roland, Gonzalez-Dunia, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219726/
https://www.ncbi.nlm.nih.gov/pubmed/22114563
http://dx.doi.org/10.1371/journal.ppat.1002393