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Dopamine D(4) receptor, but not the ADHD-associated D(4.7) variant, forms functional heteromers with the dopamine D(2S) receptor in the brain

Polymorphic variants of the dopamine D(4) receptor have been consistently associated with attention-deficit hyperactivity disorder (ADHD). However the functional significance of the risk polymorphism (variable number of tandem repeats in exon 3) is still unclear. Here we show that whereas the most f...

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Detalles Bibliográficos
Autores principales: González, Sergio, Rangel-Barajas, Claudia, Peper, Marcela, Lorenzo, Ramiro, Moreno, Estefanía, Ciruela, Francisco, Borycz, Janusz, Ortiz, Jordi, Lluís, Carme, Franco, Rafael, McCormick, Peter J., Volkow, Nora D., Rubinstein, Marcelo, Floran, Benjamin, Ferré, Sergi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219836/
https://www.ncbi.nlm.nih.gov/pubmed/21844870
http://dx.doi.org/10.1038/mp.2011.93