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Anticipation in Lynch Syndrome: Where We Are Where We Go

Lynch syndrome (LS) is the most common form of inherited predisposition to develop cancer mainly in the colon and endometrium but also in other organ sites. Germline mutations in DNA mismatch repair (MMR) gene cause the transmission of the syndrome in an autosomal dominant manner. The management of...

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Detalles Bibliográficos
Autores principales: Bozzao, Cristina, Lastella, Patrizia, Stella, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219841/
https://www.ncbi.nlm.nih.gov/pubmed/22547953
http://dx.doi.org/10.2174/138920211797904070