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Mycophenolic acid mediated mitochondrial membrane potential transition change lead to T lymphocyte apoptosis
PURPOSE: This study demonstrated that apoptosis induced by mycophenolic acid (MPA) is mediated by mitochondrial membrane potential transition (MPT) changes in Jurkat cells. METHODS: Cell viability and MPT changes were measured by flow cytometry. Western blotting was performed to evaluate the express...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Surgical Society
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219848/ https://www.ncbi.nlm.nih.gov/pubmed/22111078 http://dx.doi.org/10.4174/jkss.2011.81.4.235 |