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Mycophenolic acid mediated mitochondrial membrane potential transition change lead to T lymphocyte apoptosis

PURPOSE: This study demonstrated that apoptosis induced by mycophenolic acid (MPA) is mediated by mitochondrial membrane potential transition (MPT) changes in Jurkat cells. METHODS: Cell viability and MPT changes were measured by flow cytometry. Western blotting was performed to evaluate the express...

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Detalles Bibliográficos
Autores principales: Choi, Soo Jin Na, Lee, Ho Kyun, Kim, Nam Ho, Chung, Sang Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Surgical Society 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219848/
https://www.ncbi.nlm.nih.gov/pubmed/22111078
http://dx.doi.org/10.4174/jkss.2011.81.4.235