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Stimulatory Effect of Insulin on Glucose Uptake by Muscle Involves the Central Nervous System in Insulin-Sensitive Mice

OBJECTIVE: Insulin inhibits endogenous glucose production (EGP) and stimulates glucose uptake in peripheral tissues. Hypothalamic insulin signaling is required for the inhibitory effects of insulin on EGP. We examined the contribution of central insulin signaling on circulating insulin–stimulated ti...

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Detalles Bibliográficos
Autores principales: Coomans, Claudia P., Biermasz, Nienke R., Geerling, Janine J., Guigas, Bruno, Rensen, Patrick C.N., Havekes, Louis M., Romijn, Johannes A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219951/
https://www.ncbi.nlm.nih.gov/pubmed/22028182
http://dx.doi.org/10.2337/db10-1100