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Mapping of disease-associated variants in admixed populations

Recent developments in high-throughput genotyping and whole-genome sequencing will enhance the identification of disease loci in admixed populations. We discuss how a more refined estimation of ancestry benefits both admixture mapping and association mapping, making disease loci identification in ad...

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Detalles Bibliográficos
Autores principales: Shriner, Daniel, Adeyemo, Adebowale, Ramos, Edward, Chen, Guanjie, Rotimi, Charles N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219963/
https://www.ncbi.nlm.nih.gov/pubmed/21635713
http://dx.doi.org/10.1186/gb-2011-12-5-223