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Increased HMGB1 expression and release by mononuclear cells following surgical/anesthesia trauma
INTRODUCTION: High mobility group box 1 (HMGB1) is a key mediator of inflammation that is actively secreted by macrophages and/or passively released from damaged cells. The proinflammatory role of HMGB1 has been demonstrated in both animal models and humans, since the severity of inflammatory respon...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220009/ https://www.ncbi.nlm.nih.gov/pubmed/21044333 http://dx.doi.org/10.1186/cc9316 |