Increased HMGB1 expression and release by mononuclear cells following surgical/anesthesia trauma

INTRODUCTION: High mobility group box 1 (HMGB1) is a key mediator of inflammation that is actively secreted by macrophages and/or passively released from damaged cells. The proinflammatory role of HMGB1 has been demonstrated in both animal models and humans, since the severity of inflammatory respon...

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Detalles Bibliográficos
Autores principales: Manganelli, Valeria, Signore, Michele, Pacini, Ilaria, Misasi, Roberta, Tellan, Guglielmo, Garofalo, Tina, Lococo, Emanuela, Chirletti, Piero, Sorice, Maurizio, Delogu, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220009/
https://www.ncbi.nlm.nih.gov/pubmed/21044333
http://dx.doi.org/10.1186/cc9316

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