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Phosphorylation of the Arp2 Subunit Relieves Auto-inhibitory Interactions for Arp2/3 Complex Activation

Actin filament assembly by the actin-related protein (Arp) 2/3 complex is necessary to build many cellular structures, including lamellipodia at the leading edge of motile cells and phagocytic cups, and to move endosomes and intracellular pathogens. The crucial role of the Arp2/3 complex in cellular...

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Detalles Bibliográficos
Autores principales: Narayanan, Arjun, LeClaire, Lawrence L., Barber, Diane L., Jacobson, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220268/
https://www.ncbi.nlm.nih.gov/pubmed/22125478
http://dx.doi.org/10.1371/journal.pcbi.1002226