Cargando…

Cyclic stretch increases splicing noise rate in cultured human fibroblasts

BACKGROUND: Mechanical forces are known to alter the expression of genes, but it has so far not been reported whether they may influence the fidelity of nucleus-based processes. One experimental approach permitting to address this question is the application of cyclic stretch to cultured human fibro...

Descripción completa

Detalles Bibliográficos
Autores principales: Uhl, Michael, Mellert, Kevin, Striegl, Britta, Deibler, Martin, Lamla, Markus, Spatz, Joachim P, Kemkemer, Ralf, Kaufmann, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220655/
https://www.ncbi.nlm.nih.gov/pubmed/22040907
http://dx.doi.org/10.1186/1756-0500-4-470